I've known Katherine Isbister for quite a while now; she wrote the excellent piece on Becky Schaefer's Lara Croft-inspired needlepoint art a few years ago. Katherine has a background in the social sciences which served her well when she moved over into game design. She now has a book out -- Better Game Characters By Design: A Psychological Approach.

One of the first times I met her was when she was working at a lab in Kyoto developing an effective virtual tour guide to the city. We had interesting conversations over ramen about how information can be packaged in an emotionally charged character. She then went on to teach a course at Stanford University, where I helped judge a contest among her students for best game character design (Tim Schafer was co-judge, and that's where I met him for the first time.)

Then she moved away to upstate New York to teach at Rensselaer Polytechnic Institute, where she founded a Games research Lab. Sounds like she is doing well!